导引导丝的设计

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1、Guide Wire Design导引导丝的设计 Guide Wire Function 导丝的功能 Guide Wire Selection Goals 选择导丝时要达到的目标 Guide Wire Performance Characteristics 导丝的性能 Guide Wire Components & Design 导丝的结构和设计Guide Wire Function导丝的功能 Facilitate access to diseased vessels and the delivery of interventional equipment 协助介入器械输送至病变部位

2、Track through the vessel 在血管中走行 Access and cross lesions 到达并通过病变 Support & deliver interventional devices 支撑并输送介入器械 Steer into and protect side branches 进入并保护分支血管Guide Wire Selection Goals 选择导丝时要达到的目标 Traverse the coronary anatomy safely, independently and without damaging the vessel 安全通过冠脉血管，对血

3、管不造成损伤 Appropriate match for clinical setting 满足不同的临床需求Workhorse/front-line use 主力/一线导丝Navigate tortuous anatomy 通过迂曲血管Provide extra support 提供更强支撑力Crossing highly stenosed lesions 通过高度狭窄的病变Guide Wire Performance Characteristics导丝的性能Flexibility 柔软度Support 支撑力Steering 操控性Lubricity 顺滑度Tracking 跟踪性Torq

4、ue response 扭矩传递Visibility 可视性Tactile Feedback 触觉反馈Crossability 通过能力Performance性能Design设计 What will affect Guide Wire Performance Characteristics? 导丝的性能由何决定？ Guide Wire Components & Design导丝的结构和设计 Core Diameter 核芯直径 Core Taper 核芯椎体 Core Material 核芯材料 Tip Style 头端类型 Coils and Covers 弹簧圈和聚合物护套 Coa

5、ting 涂层Core Diameter 核芯直径 Diameter affects flexibility, support and torque 核芯直径影响导丝的柔软度、支撑力和扭矩传递Smaller Diameter = More Flexibility直径越小 = 更柔软Larger Diameter = More Support & Torque直径越大 = 支撑力更强 & 扭矩传递更好Core Taper 核芯椎体 Tracking 跟踪性Ability of wire body to follow tip around bends 导丝体部随着头端的弯曲而弯曲的

6、能力 Degree of support 支撑力的大小Core Taper 核芯椎体Longer taper 较长椎体Shorter taper较短椎体Parabolic grind流线型核芯锥体PORABOLIC GRINDGradual transitions, provide less prolapse and improves ability to follow itself into acute bends较长且过渡平缓的核芯椎体，减少导丝头端脱垂的可能性，提高导丝的跟踪性Core Taper 核芯椎体Abrupt transitions or shorter taper may r

7、esult in difficulty accessing acute angles突然变细或较短的椎体，导丝头端容易脱垂，难以通过成角的部位prolapseCore Taper 核芯椎体Core Material 核芯材料Affects flexibility, support, steering and tracking 核芯材料影响导丝的柔软度、支撑力、操控性和跟踪性Stainless Steel 不锈钢Nitinol 镍钛合金High Tensile Strength Stainless Steel 高强度不锈钢Stainless steel 不锈钢不锈钢 Original core

8、material technology 最初应用于导丝的材料 Good support, push force and torque 提供良好的支撑力、推送力和扭矩传递 Less flexible than newer core materials 与新型材料相比柔软度欠佳Core Material 核芯材料Nitinol 镍钛合金镍钛合金 Super-elastic alloy designed for kink resistance 超弹性合金，抗打折能力强 Excellent flexibility and steering 柔软度高、操控性好 Durable nature may fa